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Systemisk lupus erythematosus, SLE

Senast uppdaterad: Senast reviderad:
Sakkunnig:
Definition:
Systemisk lupus erythematosus (SLE) är en kronisk, recidiverande, inflammatorisk bindvävssjukdom med symtom från många organsystem.
Förekomst:
I Sverige är incidensen 2–3 per 100 000 och år.
Symtom:
Vanligast är utslag och ledbesvär, men man kan få symtom från njurar, luftvägar, blod, rörelseorganen och nervsystemet.
Kliniska fynd:
Kliniska fynd från många organ.
Diagnostik:
Typiska laboratoriefynd är positiv ANA, anti-dsDNA och anemi. I aktiv fas förhöjd SR.
Behandling:
hydroxiklorokin, kortison, olika cytostatika och biologiska läkemedel.
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  • Anna Nager, docent och specialist i allmänmedicin, Karolinska institutet