Whipples sjukdom
Senast reviderad:
Sakkunnig:Remy Waardenburg
Definition:
Whipples sjukdom är en infektionssjukdom som orsakas av bakterien Tropheryma whipplei.
Förekomst:
Sällsynt sjukdom med en incidens på <1/1 000 000 individer per år.
Symtom:
Olika symtom tillsammans med ospecifika fynd, i huvudsak ledsmärtor och ledinflammation. Senare uppstår viktförlust och/eller diarré och andra symtom eftersom många organ kan vara påverkade.
Kliniska fynd:
Beroende på organengagemang. Viktnedgång.
Diagnostik:
Diagnosen bekräftas med hjälp av biopsier med PAS-färgning och/eller PCR.
Behandling:
Antibiotika.
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- Remy Waardenburg, specialist i allmänmedicin, medicinsk redaktör Medibas
Tidigare sakkunniga
- Henrik Forssell, docent och överläkare, Kirurgkliniken, Blekingesjukhuset, Karlskrona