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Peroperativ trombosprofylax

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  1. Nordstrom M, Lindblad B, Bergqvist D et al. A prospective study of the incidence of deep-vein thrombosis within a defined urban population J Intern Med 1992; 232: 155-60. emedicine.medscape.com  
  2. Heit JA, O'Fallon WM, Petterson TM et al. Relative impact of risk factors for deep vein thrombosis and pulmonary embolism: a population-based study. Arch Intern Med 2002; 162: 1245-8. PubMed  
  3. Collins R, Scrimgeour A, Yusuf S et al. Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. N Engl J Med 1988; 318: 1162-73. New England Journal of Medicine  
  4. Geerts WH, Heit JA, Clagett GP et al. Prevention of venous thromboembolism. Chest 2001; 119(suppl 1): 132S-175S.
  5. White RH, Gettner S, Newman JM et al. Predictors of rehospitalization for symptomatic venous thromboembolism after total hip arthroplasty. N Engl J Med 2000; 343: 1758-64. New England Journal of Medicine  
  6. Cosmi B, Legnani C, Cini M et al. Thrombophilia and residual vein thrombosis are independent risk factors for recurrent venous thromboembolism. J Thromb Haemost 2003; (suppl 1)1: abstract OC150.
  7. Hull RD, Pineo GF, Stein PD et al. Extended out-of-hospital low-molecular-weight heparin prophylaxis against deep venous thrombosis in patients after elective hip arthroplasty: a systematic review. Ann Intern Med 2001; 135: 858-69. Annals of Internal Medicine  
  8. Raskob GE, Hirsh J. Controversies in the timing of the first dose of anticoagulant prophylaxis against venous thromboembolism after major ortopedic surgery. Chest 2003; 124(suppl): 379-85.
  9. Sachdeva A, Dalton M, Amaragiri SV, et al. Graduated compression stockings for prevention of deep vein thrombosis. Cochrane Database Syst Rev. 2014;12:CD001484. pmid: 25517473. PubMed  
  10. Wade R, Paton F, Rice S, et al. Thigh length versus knee length antiembolism stockings for the preventionof deep vein thrombosis in postoperative surgical patients; a systematic review and network meta-analysis. BMJ Open. 2016 Feb 16;6(2):e009456. pmid: 26883236. PubMed  
  11. Lassen MR, Ageno W, Borris LC, Lieberman JR. Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Total Knee Arthroplasty. N Engl J Med 2008; 358: 2776-86. PubMed  
  12. Horlocker TT, Wedel DJ, Benzon H et al. Regional anesthesia in the anticoagulated patient: defining the risks (The second ASRA consensus conference on neuraxial anesthesia and anticoagulation). Reg Anesth Pain Med 2003; 28: 172-97. PubMed  
  13. Harenberg J, Marx S, Dahl OE et al. Interpretation of endpoints in a network meta-analysis of new oral anticoagulants following total hip or total knee replacement surgery. Thromb Haemost. 2012 Nov;108(5):903-12 PubMed  
  14. Chassot PG, Delabays A. Perioperative antiplatelet therapy. Am Fam Physician 2010; 82: 1484-9. American Family Physician  
  15. Biondi-Zoccai GG, Lotrionte M, Agostoni P, et al. A systematic review and meta-analysis on the hazards of discontinuing or not adhering to aspirin among 50,279 patients at risk for coronary artery disease. Eur Heart J 2006; 27: 2667-74. European Heart Journal  
  16. Burger W, Chemnitius JM, Kneissl GD, Rücker G. Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis. J Intern Med 2005; 257: 399-414. PubMed  
  17. Moore M, Power M. Perioperative hemorrhage and combined clopidogrel and aspirin therapy. Anesthesiology 2004; 101: 792-4. PubMed  
  • Per Hellman, professor och överläkare, Kirurgkliniken, Akademiska sjukhuset, Uppsala

Tidigare sakkunniga

  • Tarjei Rygnestad, överläkare i anestesi, Klinikk Stokkan och professor med. dr, Norges teknisk-naturvitenskapelige universitet, Trondheim