Gå direkt till huvudinnehållet

Hemolytiskt-uremiskt syndrom

Senast uppdaterad: Publicerad:
Sakkunnig:


  1. Razzaq S. Hemolytic uremic syndrome: An emerging health risk. Am Fam Physician 2006; 74: 991-6. PubMed  
  2. Tarr PI, Gordon CA, Chandler WL. Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome. Lancet 2005; 365: 1073-86. PubMed  
  3. Andreoli SP. The pathophysiology of the hemolytic uremic syndrome. Curr Opin Nephrol Hypertens 1999; 8: 459-64. PubMed  
  4. Index of suspicion. Pediatr Rev 2002; 23: 433-8. PubMed  
  5. Williams DM, Sreedhar SS, Mickell JJ, Chan JC. Acute kidney failure: a pediatric experience over 20 years. Arch Pediatr Adolesc Med 2002; 156: 893-900. PubMed  
  6. Klein EJ, Stapp JR, Clausen CR, et al. Shiga toxin-producing Escherichia coli in children with diarrhea: a prospective point of care study. J Pediatr 2002; 141: 172-77. PubMed  
  7. Andreoli SP. Acute renal failure. Curr Opin Pediatr 2002; 14: 183-8. PubMed  
  8. Wong CS, Jelacic S, Habeeb RL, Watkins SL, Tarr PI. The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections. N Engl J Med 2000; 342: 1930-6. PubMed  
  9. Chandler WL, Jelacic B, Boster DR, et al. Prothrombotic coagulation abnormalities associated with Escherichia coli O157:H7 infections. N Engl J Med 2002; 346: 23-32. PubMed  
  10. Piercefield EW, Bradley KK, Coffman RL, Mallonee SM. Hemolytic uremic syndrome after an Eschericia coli O111 outbreak. Arch Intern Med 2010; 170: 1656-63. PubMed  
  11. Crump JA, Sulka AC, Langer AJ, Schaben C, Crielly AS, Gage R, et al. An outbreak of Escherichia coli O157:H7 infections among visitors to a dairy farm. N Engl J Med 2002; 347: 555-60. New England Journal of Medicine  
  12. Haack JP, Jelacic S, Besser TE, Weinberger E, Kirk DJ, McKee GL, et al. Escherichia coli O157 exposure in Wyoming and Seattle: serologic evidence of rural risk. Emerg Infect Dis 2003; 9: 1226-31. PubMed  
  13. Boyce TG, Swerdlow DL, Griffin PM. Escherichia coli O157:H7 and the hemolytic-uremic syndrome. N Engl J Med 1995; 333: 364-8. New England Journal of Medicine  
  14. Fitzpatrick M. BMJ Editorial 1999;318: 684-5 PubMed  
  15. Rowe PC et al. Risk of hemolytic uremic syndrome after spradic Eschericia coli 0157:H7 infection. J Pediatr 1998; 132: 777-82 PubMed  
  16. Chang HG, Tserenpuntsag B, Kacica M, Smith PF, Morse DL. Hemolytic uremic syndrome incidence in New York. Emerg Infect Dis 2004; 10: 928-31. PubMed  
  17. Wong CS, Jelacic S, Habeeb RL, Watkins SL, Tarr PI. The risk of the Hemlytic-Uremic Syndrome after antibiotic treatment og eschericia coli O157:H7 infections. N Engl J Med 2000; 342: 1930-6. New England Journal of Medicine  
  18. Bell BP, Goldoft M, Griffin PM, et al. A multistate outbreak of Escherichia coli O157:H7 associated bloody diarrhea and hemolytic uremic syndrome from hamburgers: the Washington experience. JAMA 1994; 272: 1349-53. PubMed  
  19. Baylis CL, MacPhee S, Robinson AJ, Griffiths R, Lilley K, Betts RP. Survival of Escherichia coli O157:H7, O111:H- and O26:H11 in artificially contaminated chocolate and confectionery products. Int J Food Microbiol 2004; 96: 35-48. PubMed  
  20. Richardson SE, Karmali MA, Becker LE, Smith CR. The histopathology of the hemolytic uremic syndrome associated with verocytotoxin-producing Escherichia coli infections. Hum Pathol 1998; 19: 1102-08.
  21. Thorpe CM. Shiga toxin-producing Escherichia coli infection. Clin Infect Dis 2004; 38: 1298-303. PubMed  
  22. Katz J, Lurie A, Kaplan BS, Krawitz S, Metz J. Coagulation findings in the hemolytic-uremic syndrome of infancy: similarity to hyperacute renal allograft rejection. J Pediatr 1971; 78: 426-34. PubMed  
  23. Slutsker L, Ries AA, Maloney K, Wells JG, Greene KD, Griffin PM. A nationwide case-control study of Escherichia coli O157:H7 infection in the United States. J Infect Dis 1998; 177: 962-6. PubMed  
  24. Slutsker L, Ries AA, Greene KD, Wells JG, Hutwagner L, Griffin PM. Escherichia coli O157:H7 diarrhea in the United States: clinical and epidemiologic features. Ann Intern Med 1997; 126: 505-13. PubMed  
  25. Siegler RL. Spectrum of extrarenal involvement in postdiarrheal hemolytic-uremic syndrome. J Pediatr 1994; 125: 511. PubMed  
  26. March SB, Tarnam S. Sorbitol-MacConkey medium for detection of Escherichia coli O157:H7 associated with hemorrhagic colitis. J Clin Microbiol 1986; 23: 869-72. PubMed  
  27. Michael M, Elliot EJ, Ridley GF, et al. Interventions for hemolytic uraemic syndrome and thrombotic thrombocytogenic purpura. Cochrane Database Syst Rev 2009; 1: CD003595. Cochrane (DOI)  
  28. Garg AX, Suri RS, Barrowman N, Rehman F, Matsell D, Rosas-Arellano MP, et al. Long-term renal prognosis of diarrhea-associated hemolytic uremic syndrome: a systematic review, meta-analysis, and meta-regression. JAMA 2003; 290: 1360-70. Journal of the American Medical Association  
  29. Brandt JR, Fouser LS, Watkins SL, et al. Escherichia coli O157:H7-associated hemolytic-uremic syndrome after ingestion of contaminated hamburgers. J Pediatr 1994; 125: 519-26. PubMed  
  30. Hughes DA, Beattie TJ, Murphy AV. Haemolytic uraemic syndrome: 17 years' experience in a Scottish paediatric renal unit. Scott Med J 1991; 36: 9-12. PubMed  
  31. Brandt JR, Joseph MW, Fouser LS, et al. Cholelithiasis following Escherichia coli O157:H7-associated hemolytic uremic syndrome. Pediatr Nephrol 1998; 12: 222-5. PubMed  
  32. Garg AX, Suri RS, Barrowman N, et al. Long-term renal prognosis of diarrhea-associated hemolytic uremic syndrome: a systematic review, meta-analysis, and meta-regression. JAMA 2003; 290: 1360-70. Journal of the American Medical Association  
  33. Garg AX, Clark WF, Salvadori M, Thiessen-Philbrook HR, Matsell D. Absence of renal sequelae after childhood Escherichia coli O157:H7 gastroenteritis. Kidney Int 2006; 70: 807-12. PubMed  
  34. Bell BP, Griffin PM, Lozano P, Christie DL, Kobayashi JM, Tarr PI. Predictors of hemolytic uremic syndrome in children during a large outbreak of Escherichia coli O157:H7 infections. Pediatrics 1997; 100: E12. PubMed  
  35. Corrigan Jr JJ, Boineau FG. Hemolytic-uremic syndrome. Pediatr Rev 2001; 22: 365-9. PubMed  
  36. Phillips B, Tyerman K, Whiteley SM. Use of antibiotics in suspected haemolytic-uraemic syndrome. BMJ 2005; 330: 409-10. PubMed  
  • Nils Grefberg, med dr och överläkare internmedicin och nefrologi, tidigare vid medicinkliniken, Centrallasarettet Växjö