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Hirsutism

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  1. Hunter MH, Carek PJ. Evaluation and treatment of women with hirsutism. Am Fam Physician 2003; 67: 2565-72. PubMed  
  2. Redmond GP, Bergfeld WF. Diagnostic approach to androgen disorders in women: acne, hirsutism, and alopecia. Cleve Clin J Med 1990;57:423-7. PubMed  
  3. Rittmaster RS. Clinical relevance of testosterone and dihydrotestosterone metabolism in women. Am J Med 1995;98(1A):17S-21S.
  4. Givens JR, Kurtz BR. Hirsutism, virilization, and androgen excess. In: Hurst JW, Ambrose SS, et al., eds. Medicine for the practicing physician. 3d ed. Boston: Butterworth-Heinemann, 1992:568-71.
  5. Rosenfield RL. Hirsutism. N Engl J Med 2005; 353: 2578-88. PubMed  
  6. Leung AK, Robson WL. Hirsutism. Int J Dermatol 1993;32:773-7. PubMed  
  7. Gilchrist VJ, Hecht BR. A practical approach to hirsutism. Am Fam Physician 1995;52:1837-46. PubMed  
  8. Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab 1998; 83: 3078-82. PubMed  
  9. Deplewski D, Rosenfield RL. Role of hormones in pilosebaceous unit development. Endocr Rev 2000; 21: 363-92. PubMed  
  10. Rosner W. The functions of corticosteroid-binding globulin and sex hormone binding-globulin: recent advances. Endocr Rev 1990; 11: 80-91. PubMed  
  11. Nestler JE, Powers LP, Matt DW, et al. A direct effect of hyperinsulinemia on serum sex-hormone binding globulin levels in obese women with the polycystic ovary syndrome. J Clin Endocrinol Metab 1991; 72: 83-9. PubMed  
  12. Hogeveen KN, Cousin P, Pugeat M, Dewailly D, Soudan B, Hammond GL. Human sex hormone-binding globulin variants associated with hyperandrogenism and ovarian dysfunction. J Clin Invest 2002; 109: 973-81. PubMed  
  13. Reingold SB, Rosenfield RL. The relationship of mild hirsutism or acne in women to androgens. Arch Dermatol 1987; 123: 209-12. PubMed  
  14. Griffing GT, Melby JC. Hirsutism causes and treatments. Hosp Pract (Off Ed) 1991;26(5A):43-58.
  15. Franks S. Polycystic ovary syndrome. N Engl J Med 1995;333:853-61 (Published erratum appears in N Engl J Med 1995;333:1435).
  16. Ehrmann DA. Polycystic ovary syndrome. N Engl J Med 2005; 352: 1223-36. New England Journal of Medicine  
  17. Dunaif A, Segal KR, Shelley DR, Green G, Dobrjansky A, Licholai T. Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndrome. Diabetes 1992;41:1257-66. PubMed  
  18. Azziz R, Sanchez LA, Knochenhauer ES, et al. Androgen excess in women: experience with over 1000 consecutive patients. J Clin Endocrinol Metab 2004; 89: 453-62. PubMed  
  19. Ehrmann DA, Rosenfield RL, Barnes RB, Brigell DF, Sheikh Z. Detection of functional ovarian hyperandrogenism in women with androgen excess. N Engl J Med 1992; 327: 157-62. New England Journal of Medicine  
  20. Deaton MA, Glorioso JE, McLean DB. Congenital adrenal hyperplasia: not really a zebra. Am Fam Physician 1999;59:1190-6. PubMed  
  21. Kaltsas GA, Isidori AM, Kola BP, et al. The value of the low-dose dexamethasone suppression test in the differential diagnosis of hyperandrogenism in women. J Clin Endocrinol Metab 2003; 88: 2634-43. PubMed  
  22. New MI, Rapaport R. The adrenal cortex. In: Sperling MA, ed. Pediatric endocrinology. Philadelphia: Saunders, 1996:281-314.
  23. Souter I, Sanchez LA, Perez M, Bartolucci AA, Azziz R. The prevalence of androgen excess among patients with minimal unwanted hair growth. Am J Obstet Gynecol 2004; 191: 1914-20. PubMed  
  24. Rosenfield RL, Cohen RM, Talerman A. Lipid cell tumor of the ovary in reference to adult-onset congenital adrenal hyperplasia and polycystic ovary syndrome: a case report. J Reprod Med 1987; 32: 363-9. PubMed  
  25. ACOG technical bulletin. Evaluation and treatment of hirsute women. Number 203--March 1995 (replaces no. 103, April 1987). American College of Obstetricians and Gynecologists. Int J Gynaecol Obstet 1995;49:341-6. PubMed  
  26. Carmina E, Lobo RA. Peripheral androgen blockade versus glandular androgen suppression in the treatment of hirsutism. Obstet Gynecol 1991;78(5 Pt 1):845-9.
  27. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 2004; 81: 19-25. PubMed  
  28. Azziz R. Diagnostic criteria for polycystic ovary syndrome: a reappraisal. Fertil Steril 2005; 83: 1343-6. PubMed  
  29. Wajchenberg BL, Albergaria Pereira MA, Medonca BB, et al. Adrenocortical carcinoma: clinical and laboratory observations. Cancer 2000; 88: 711-36. PubMed  
  30. Speroff L, Glass RH, Kase NG, eds. Clinical gynecologic endocrinology and infertility. 6th ed. Baltimore: Lippincott Williams & Wilkins, 1999:529-56.
  31. Azziz R. The evaluation and management of hirsutism. Obstet Gynecol 2003; 101: 995-1007. PubMed  
  32. Balfour JA, McClellan K. Topical eflornithine. Am J Clin Dermatol 2001; 2: 197-201. PubMed  
  33. Dierickx CC. Hair removal by lasers and intense pulsed light sources. Dermatol Clin 2002; 20: 135-146. PubMed  
  34. Battle EF Jr, Hobbs LM. Laser-assisted hair removal for darker skin types. Dermatol Ther 2004; 17: 177-83. PubMed  
  35. Martin KA, Chang RJ, Ehrmann DA, et al. Evaluation and treatment of hirsutism in premenopausal women: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2008; 93: 1105-20. PubMed  
  36. Begränsningar i användningen av cyproteron på grund av risk för meningeom. Nyheter 2020-02-19 lakemedelsverket.se  
  37. Farquhar C, Lee O, Toomath R, Jepson R. Spironolacton versus placebo or in combination with steroids for hirsutisme and/or acne. Cochrane Database Syst Rev 2003; 4: CD000194. Cochrane (DOI)  
  38. Swiglo BA, Cosma M, Flynn DN, et al. Antiandrogens for the treatment of hirsutism: a systematic review and metaanalyses of randomized controlled trials. J Clin Endocrinol Metab 2008; 93: 1153-60. PubMed  
  39. Hancock KW, Levell MJ. The use of oestrogen-progestogen preparations in the treatment of hirsutism in the female. J Obstet Gynaecol Br Commonw 1974; 81: 804-11. PubMed  
  40. Heiner JS, Greendale GA, Kawakami AK, et al. Comparison of a gonadotropin-releasing hormone agonist and a low dose oral contraceptive given alone or together in the treatment of hirsutism. J Clin Endocrinol Metab 1995; 80: 3412-8. PubMed  
  • Cecilia Mattsson, docent och överläkare, Endokrinsektionen, Medicinkliniken, Norrlands universitetssjukhus, Umeå

Tidigare sakkunniga

  • John Cooper, specialist i allmänmedicin och invärtes medicin, Medicinsk avdelning, Centralsjukhuset i Rogaland, Stavanger
  • Stein Vaaler, överläkare med. dr., Center för Klinisk Epidemiologi, Rikshospitalet, Universitetet i Oslo