Gå direkt till huvudinnehållet

Förebygga allergier

Senast uppdaterad: Senast reviderad:
Sakkunnig:

  1. Caffarelli C, Garrubba M, Greco C, Mastrorilli C, Povesi Dascola C. Asthma and Food Allergy in Children: Is There a Connection or Interaction?. Front Pediatr. 2016;4:34. Published 2016 Apr 5. doi:10.3389/fped.2016.00034 DOI  
  2. Fontanella S, Frainay C, Murray CS, Simpson A, Custovic A. Machine learning to identify pairwise interactions between specific IgE antibodies and their association with asthma: A cross-sectional analysis within a population-based birth cohort. PLoS Med. 2018;15(11):e1002691. Published 2018 Nov 13. doi:10.1371/journal.pmed.1002691 DOI  
  3. Westman, M., Asarnoj, A., Hamsten, C., Wickman, M., & van Hage, M. (2017). Windows of opportunity for tolerance induction for allergy by studying the evolution of allergic sensitization in birth cohorts. Seminars in Immunology, 30, 61–66. doi:10.1016/j.smim.2017.07.005 DOI  
  4. Munblit D, Peroni DG, Boix-Amorós A et al. Human Milk and Allergic Diseases: An Unsolved Puzzle. Nutrients. 2017 Aug 17;9(8). pii: E894. doi: 10.3390/nu9080894. DOI  
  5. Lloyd-Lavery, A., Rogers, N. K., Davies, E., Grindlay, D. J. C., & Thomas, K. S. (2018). What’s new in atopic eczema? An analysis of systematic reviews published in 2015. Part 2: prevention and treatment. Clinical and Experimental Dermatology, 43(6), 653–658. doi:10.1111/ced.13554 DOI  
  6. Oszukowska M, Michalak I, Gutfreund K, et al. Role of primary and secondary prevention in atopic dermatitis. Postepy Dermatol Alergol. 2015;32(6):409–420. doi:10.5114/pdia.2014.44017 DOI  
  7. Dogaru CM, Nyffenegger D, Pescatore AM, et al. Breastfeeding and childhood asthma: systematic review and meta-analysis. Am J Epidemiol 2014; 179: 1153-67. doi:10.1093/aje/kwu072 DOI  
  8. Jelding-Dannemand E, Malby Schoos AM, Bisgaard H. Breast-feeding does not protect against allergic sensitization in early childhood and allergy-associated disease at age 7 years. J Allergy Clin Immunol 2015; 136: 1302-08. pmid:25843315 PubMed  
  9. Silano M, Agostoni C, Sanz Y, Guandalini S. Infant feeding and risk of developing celiac disease: a systematic review. BMJ Open. 2016 Jan 25;6(1):e009163. doi: 10.1136/bmjopen-2015-009163. DOI  
  10. Chmielewska A, Pieścik‐Lech M, Shamir R, Szajewska H. Systematic review: Early infant feeding practices and the risk of wheat allergy 2017 Sep;53(9):889-896. doi: 10.1111/jpc.13562 DOI  
  11. Lodge, C., Tan, D., Lau, M., Dai, X., Tham, R., Lowe, A., … Dharmage, S. (2015). Breastfeeding and asthma and allergies: a systematic review and meta-analysis. Acta Paediatrica, 104, 38–53. doi:10.1111/apa.13132 DOI  
  12. Livsmedelsverket och Barnläkarföreningens delförening för allergi och lungmedicin. Pressmeddelande. Bra attlåta spädbarn smaka alltyp avmat underförsta året. Publicerat 2020-06. Hämtad 2020-11-06. medibas.se  
  13. Toit GD, Roberts G, Sayre PH, et al. Randomized trial pf peanut comsumption infants at risk for peanut allergy. N Engl J Med 2015; 372: 803-13. doi:10.1056/NEJMoa1414850 DOI  
  14. Toit GD, Sayre PH, Roberts G, et al. Effect of avoidance on peanut allergy after early peanut consumption. N Engl J Med 2016. doi:10.1056/NEJMoa1514209 DOI  
  15. Greenhawt M. The Learning Early About Peanut Allergy Study: The Benefits of Early Peanut Introduction, and a New Horizon in Fighting the Food Allergy Epidemic. Pediatr Clin North Am. 2015 Dec;62(6):1509-21. doi: 10.1016/j.pcl.2015.07.010.
  16. Katz Y, Rajuan N, Goldberg MR, et al. Early exposure to cow's milk protein is protective against IgE-mediated cow's milk protein allergy. J Allergy Clin Immunol 2010; 126: 77-82.e1. doi:10.1016/j.jaci.2010.04.020 DOI  
  17. Perkin MR, Logan K, Tseng A, et al . Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants. N Engl J Medicine 2016. doi:10.1056/NEJMoa1514210 DOI  
  18. Pinto-Sánchez MI et al. Gluten Introduction to Infant Feeding and Risk of Celiac Disease: Systematic Review and Meta-Analysis. J Pediatr. 2016 Jan;168:132-43.e3. doi: 10.1016/j.jpeds.2015.09.032 DOI  
  19. Vriezinga SL, Auricchio R, Bravi E, et al. Randomized feeding intervention in infants at high risk for celiac disease. N Engl J Med 2014;371:1304-1315 New England Journal of Medicine  
  20. Osborn DA, Sinn JKH. Prebiotics in infants for prevention of allergy. Cochrane Database of Systematic Reviews 2013, Issue 3. Art. No.: CD006474. DOI: 10.1002/14651858.CD006474.pub3. DOI  
  21. Miles EA, Calder PC. Can Early Omega-3 Fatty Acid Exposure Reduce Risk of Childhood Allergic Disease?. Nutrients. 2017;9(7):784. Published 2017 Jul 21. doi:10.3390/nu9070784 DOI  
  22. Gøtzsche PC, Johansen HK. House dust mite control measures for asthma. Cochrane Database of Systematic Reviews 2008, Issue 2. Art. No.: CD001187. DOI: 10.1002/14651858.CD001187.pub3. DOI  
  23. Nankervis H, Pynn EV, Boyle RJ, Rushton L, Williams HC, Hewson DM, Platts‐Mills T. House dust mite reduction and avoidance measures for treating eczema. Cochrane Database of Systematic Reviews 2015, Issue 1. Art. No.: CD008426. DOI: 10.1002/14651858.CD008426.pub2. DOI  
  24. Strzelak A, Ratajczak A, Adamiec A, Feleszko W. Tobacco Smoke Induces and Alters Immune Responses in the Lung Triggering Inflammation, Allergy, Asthma and Other Lung Diseases: A Mechanistic Review. Int J Environ Res Public Health. 2018;15(5):1033. Published 2018 May 21. doi:10.3390/ijerph15051033 DOI  
  25. Villeneuve, C., Kou, H. H., Eckermann, H., Palkar, A., Anderson, L. G., McKenney, E. A., … Parker, W. (2018). Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications? Microbes and Infection, 20(3), 147–155. doi:10.1016/j.micinf.2017.11.001 DOI  
  26. Alexandre-Silva, G. M., Brito-Souza, P. A., Oliveira, A. C. S., Cerni, F. A., Zottich, U., & Pucca, M. B. (2018). The hygiene hypothesis at a glance: Early exposures, immune mechanism and novel therapies. Acta Tropica, 188, 16–26. doi:10.1016/j.actatropica.2018.08.032 DOI  
  27. Calderón, M. A., Kleine-Tebbe, J., Linneberg, A., De Blay, F., Hernandez Fernandez de Rojas, D., Virchow, J. C., & Demoly, P. (2015). House Dust Mite Respiratory Allergy: An Overview of Current Therapeutic Strategies. The Journal of Allergy and Clinical Immunology: In Practice, 3(6), 843–855. doi:10.1016/j.jaip.2015.06.019 DOI  
  28. Abramson MJ, Puy RM, Weiner JM. Injection allergen immunotherapy for asthma. Cochrane Database of Systematic Reviews 2010, Issue 8. Art. No.: CD001186. DOI: 10.1002/14651858.CD001186.pub2. DOI  
  29. Mener DJ, Lin SY. The role of allergy immunotherapy in the treatment of asthma. Curr Opin Otolaryngol Head Neck Surg. 2016 Jun;24(3):215-20. doi: 10.1097/MOO.0000000000000249. DOI  
  30. Wahn U, ETAC Study Group. Allergic factors associated with the development of asthma and the influence of cetirizine in a double-blind, randomised, placebo-controlled trial: First results of ETAC. Pediatr Allergy Immunol 1998; 9: 116-24. PubMed  
  31. Greer FR, Sicherer SH, Burks AW; American Academy of Pediatrics Committee on Nutrition; American Academy of Pediatrics Section on Allergy and Immunology. Effects of early nutritional interventions on the development of atopic disease in infants and children: The role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas. Pediatrics 2008; 121: 183-91. Pediatrics  
  32. Iikura Y, Naspitz CM, Mikawa H et al. Prevention of asthma by ketotifen in infants with atopic dermatitis. Ann Allergy 1992; 68: 233-6. PubMed  
  33. Moller C, Dreborg S, Ferdousi HA et al. Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study). J Allergy Clin Immunol 2002; 109: 251-6. PubMed  
  34. Abramson MJ, Puy RM, Weiner JM. Allergen immunotherapy for asthma. Cochrane Database Syst Rev 2000, Issue 2. CD001186. Cochrane (DOI)  
  35. Asher I, Boner A, Chuchalin A et al. Prevention of allergy and asthma: interim report. Allergy 2000; 55: 1069-88. PubMed  
  36. Gotzsche PC, Johansen HK, Burr ML et al. House dust mite control measures for asthma (Cochrane Review). Cochrane Database Syst Rev 2001, Issue 3. The Cochrane Library  
  37. Custovic A, Simpson A, Chapman MD et al. Allergen avoidance in the treatment of asthma and atopic disorders. Thorax 1998; 53: 63-72. PubMed  
  38. Halken S, Host A, Niklassen U et al. Effect of mattress and pillow encasings on children with asthma and house dust mite allergy. J Allergy Clin Immunol 2003; 111: 169-76. PubMed  
  39. WHO. Prevention of Allergy and Allergic Asthma. Based on the WHO/WAO Meeting on the Prevention of allergy and Allergic Asthma. http://www.worldallergy.org/professional/who_paa2003.pdf, oktober 2004.
  40. Host A, Andrae S, Charkin S et al. Allergy testing in children: why, who, when and how? Allergy 2003; 58: 559-69. PubMed  
  41. Strachan DP. Hayfever, hygiene, and household size. BMJ 1989; 299: 1259-60. British Medical Journal  
  42. Strachan DP. Family size, infection and atopy: the first decade of the ''hygiene hypothesis''. Thorax 2000; 55 (suppl 1): S2-S10.
  43. Rautava S, Ruuskanen O, Ouwehand A et al. The hygiene hypothesis of atopic disease - an extended version. J Pediatr Gastroenterol Nutr 2004; 38: 378-88. PubMed  
  44. Agostoni C, Axelsson I, Braegger C et al. Probiotic bacteria in dietetic products for infants: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr 2004; 38: 365-74. PubMed  
  45. Viljanen M, Savilahti E, Haahtela T, et al. Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double-blind placebo-controlled trial. Allergy 2005; 60: 494-500. PubMed  
  46. Strachan DP, Cook DG. Health effects of passive smoking. Thorax 1997; 52: 905-14. PubMed  
  47. Strachan DP, Cook DG. Parental smoking and childhood asthma: longitudinal and case-control studies. Thorax 1998; 53: 204-12. PubMed  
  48. Cook DG, Strachan DP. Summary of effect of parental smoking on the respiratory health of children and implications for research. Thorax 1999; 54: 357-66. PubMed  
  49. Lodrup Carlsen KC, Carlsen KH. Effects of maternal and early tobacco exposure on the development of asthma and airway hyperreactivity. Curr Opin Allergy Clin Immunol 2001; 1: 139-43. PubMed  
  50. Ulrik CS, Backer V. Increased bronchial responsiveness to exercise as a risk factor for symptomatic asthma: findings from a longitudinal population study of children and adolescents. Eur Respir J 1996; 9: 1696-700. PubMed  
  51. Muraro A, Dreborg S, Halken S et al. Dietary prevention of allergic diseases in infants and small children. Part III: Criterial review of published peer-reviewed observational and interventional studies and final recommendations. Pediatr Allergy Immunol 2004; 15: 291-307. PubMed  
  52. Sears MR, Greene JM, Willan AR, et al. Long-term relation between breastfeeding and development of atopy and asthma in children and young adults: a longitudinal study. Lancet 2002; 360: 901. pmid:12354471 PubMed  
  53. Lionetti E, Castellaneta S, Francavilla R, et al. Introduction of gluten, HLA status, and the risk of celiac disease in children. N Engl J Med 2014;371:1295-1303. New England Journal of Medicine  
  54. Hoyt AE, Medico T, Commins SP. Breast Milk and Food Allergy: Connections and Current Recommendations. Pediatr Clin North Am. 2015;62:1493-507. pmid:26456446 PubMed  
  55. Azad MB, Coneys JG, Kozyrskyj AL, et al. Probiotic supplementation during pregnanacy or infancy for the prevention of asthma and wheeze: systematic review and meta-analysis. BMJ 2013; 347: f6471. doi:10.1136/bmj.f6471 DOI  
  56. Muraro A, Dreborg S, Halken S et al. Dietary prevention of allergic diseases in infants and small children. Part I: Immunologic background and criteria for hypoallergenicity. Pediatr Allergy Immunol 2004; 15: 103-11. PubMed  
  57. Hansen LG, Halken S, Høst A et al. Prediction of allergy from family history and cord blood IgE levels. A follow-up at the age of 5 years. Cord blood IgE IV. Allergy Immunol 1993; 4: 34-40. PubMed  
  58. Halken S. Early sensitisation and development of allergic airway disease - risk factors and predictors. Paediatr Respir Rev 2003; 4: 128-34. PubMed  
  59. Halken S, Backer V. Allergiprofylakse. Ugeskr Læger 2005; 167: 656-60. PubMed  
  60. Bornehag CG, Sundell J, Hagerhed L et al. Pet-keeping in early childhood and airway, nose and skin symptoms later in life. Allergy 2003; 58: 939-44. PubMed  
  61. Høst A, Halken S, Poulsen LK. Miljøfaktorers betydning for udvikling af allergi. Ugeskr Læger 2005; 167: 613-6. PubMed  
  62. Custovic A, Simpson BM, Simpson A et al. Effect of environmental manipulation in pregnancy and early life on respiratory symptoms and atopy during first year of life: a randomised trial. Lancet 2001; 358: 188-93. PubMed  
  63. Halken S, Høst A. The lessons of noninterventional and interventional prospective studies on the development of atopic disease during childhood. Allergy 2000; 55: 793-802. PubMed  
  64. Van Odijk J, Kull I, Borres MP et al. Breastfeeding and allergic disease: a multidisciplinary review of the literature (1966-2001) on the mode of early feeding in infancy and its impact on later atopic manifestations. Allergy 2003; 58: 833-43. PubMed  
  65. Ulrik CS, Backer V. Longitudinal determinants of bronchial responsiveness to inhaled histamine. Chest 1998; 113: 973-9. PubMed  
  66. Lucas A, Brooke OG, Morley R et al. Early diet of preterm infants and development of allergic or atopic disease: randomized prospective study. BMJ 1990; 300: 837-40. British Medical Journal  
  67. Yang YW, Tsai CL, Lu CY. Exclusive breastfeeding and incident atopic dermatitis in childhood: a systematic review and meta-analysis of prospective cohort studies. Br J Dermatol 2009; 161: 373-83. pmid:19239469 PubMed  
  68. Celedon JC, Litonjua AA, Ryan L et al. Exposure to cat allergen, maternal history of asthma, and wheezing in first 5 years of life. Lancet 2002; 360: 781-2. PubMed  
  69. Arshad SH, Bateman B, Matthews SM. Primary prevention of asthma and atopy during childhood by allergen avoidance in infancy: a randomised controlled study. Thorax 2003; 58: 489-93. PubMed  
  70. Kukkonen K, Savilahti E, Haahtela T, et al. Long-term safety and impact on infection rates of postnatal probiotic and prebiotic (synbiotic) treatment: randomized, double-blind, placebo-controlled trial. Pediatrics 2008; 122: 8-12. Pediatrics  
  71. Host A, Halken S. Can we apply clinical studies to real life? Evidence based recommendations from studies on development on allergic diseases and allergy prevention. Allergy 2002; 57: 389-97. PubMed  
  72. Osborn DA, Sinn J. Formulas containing hydrolysed protein for prevention of allergy and food intolerance in infants. (Cochrane Review). In: The Cochrane Library, Issue 4, 2003. The Cochrane Library  
  73. Sicherer S, Sampson H. Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management. 2018, Journal of Allergy and Clinical Immunology 141(1),41–58 doi.org  
  74. Lee JH, Son SW, Cho SH. A Comprehensive Review of the Treatment of Atopic Eczema. Allergy Asthma Immunol Res. 2016;8(3):181–190. doi:10.4168/aair.2016.8.3.181 DOI  
  • Athena Adeli, legitimerad läkare, Karolinska Institutet

Tidigare sakkunniga

  • Theo Gülen Biträdande överläkare, Lung- och allergikliniken, Karolinska universitetssjukhuset